CGPH FACULTY: Julia Walsh
DATE OF PUBLICATION: December 2013
REGION: Africa
REFERENCE: Verguet S, Stalcup M, Walsh JA. Where to deploy pre-exposure prophylaxis (PrEP) in sub-Saharan Africa? Sex Transm Infect. 2013 Dec;89(8):628-34. doi: 10.1136/sextrans-2012-050891. Epub 2013 Aug 2. Review.
SUMMARY/ABSTRACT: Two randomised controlled trials showed that pre-exposure prophylaxis (PrEP) reduces HIV transmission between heterosexual men and women. We model the potential impact on transmission and cost-effectiveness of providing PrEP in sub-Saharan Africa. In a general adult population, PrEP is a high-cost intervention which will have maximum impact and be cost-effective only in countries that have high levels of HIV burden and low levels of male circumcision in the population. Hence, PrEP will likely be most effective in Southern Africa as a targeted intervention added to existing strategies to control the HIV pandemic
ACCESS: Link to Pubmed