CGPH FACULTY: Lee Riley
DATE OF PUBLICATION: January 2014
REGION: South America
REFERENCE: Berman H, Barberino MG, Moreira ED Jr, Riley L, Reis JN. J Clin Microbiol. Distribution of strain type and antimicrobial susceptibility of Escherichia coli causing meningitis in a large urban setting in Brazil. 2014 Feb 12.
SUMMARY/ABSTRACT: The clinical management of meningitis caused by Escherichia coli is greatly complicated when the organism becomes resistant to broad-spectrum antibiotics. We sought to characterize the antimicrobial susceptibility, sequence type (ST), and presence of known drug resistance genes of E. coli that caused meningitis between 1996 and 2011 in Salvador, Brazil. These observations demonstrate that compared to E. coli isolated from cases of community acquired urinary tract infections those isolated from cases of meningitis are more resistant to third-generation cephalosporins even though the same sequence types are shared between the two forms of extraintestinal infections.
ACCESS: Link to Pubmed