Clinical presentation, etiology, and survival in adult acute encephalitis syndrome in rural Central India

/ / Faculty Research in Asia, Research

CGPH FACULTY: John Colford, Art Reingold

DATE OF PUBLICATION: September 2013

REGION: Global

REFERENCE: Joshi R, Mishra PK, Joshi D, Santhosh SR, Parida MM, Desikan P, Gangane N, Kalantri SP, Reingold A, Colford JM Jr. Clinical presentation, etiology, and survival in adult acute encephalitis syndrome in rural Central India. Clin Neurol Neurosurg. 2013 Sep;115(9):1753-61. doi: 10.1016/j.clineuro.2013.04.008.

SUMMARY/ABSTRACT: Acute encephalitis syndrome (AES) is a constellation of symptoms that includes fever and altered mental status. Most cases are attributed to viral encephalitis (VE), occurring either in outbreaks or sporadically. We conducted hospital-based surveillance for sporadic adult-AES in rural Central India in order to describe its incidence, spatial and temporal distribution, clinical profile, etiology and predictors of mortality.This study is the first description of the etiology of adult-AES in India, and provides a framework for future surveillance programs in India.

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