The Nicaraguan pediatric dengue cohort study: incidence of inapparent and symptomatic dengue virus infections, 2004-2010

/ / Faculty Research in Latin America, Research

CGPH FACULTY: Aubree Gordon, Eva Harris

DATE OF PUBLICATION: September 2013

REGION: Central America (Nicaragua)

REFERENCE: Gordon A, Kuan G, Mercado JC, Gresh L, Avilés W, Balmaseda A, Harris E. The nicaraguan pediatric dengue cohort study: incidence of inapparent and symptomatic dengue. PLoS Negl Trop Dis. 2013 Sep 26;7(9):e2462.  virus infections, 2004-2010.

SUMMARY/ABSTRACT: Dengue, caused by the four serotypes of dengue virus (DENV), is the most prevalent mosquito-borne viral disease of humans. To examine the incidence and transmission of dengue, the authors performed a prospective community-based cohort study in 5,545 children aged 2-14 years in Managua, Nicaragua, between 2004 and 2010. Children were provided with medical care through study physicians who systematically recorded medical consult data, and yearly blood samples were collected to evaluate DENV infection incidence.

ACCESS: Link to Pubmed