CGPH FACULTY: Eva Harris
DATE OF PUBLICATION: March 2014
REGION: Global
REFERENCE: Waggoner JJ, Abeynayake J, Balassiano I, Lefterova M, Sahoo MK, Liu Y, Vital-Brazil JM, Gresh L, Balmaseda A, Harris E, Banaei N, Pinsky BA. A Multiplex Nucleic Acid Amplification Test for the Diagnosis of Dengue, Malaria, and Leptospirosis. J Clin Microbiol.2014 Mar 26.
SUMMARY/ABSTRACT: Dengue, leptospirosis, and malaria are among the most common etiologies of an undifferentiated, systemic febrile illness (UFI) among travelers to the developing world, and these pathogens all have the potential to cause a life-threatening illness in the returned traveler. The current study describes the development of an internally-controlled, multiplex nucleic acid amplification test for the detection of dengue virus (DENV), Leptospira, and Plasmodium species, with a specific call-out for P. falciparum (referred to as the UFI assay).
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