Are Hormonal Contraceptive Users More Likely to Misreport Unprotected Sex? Evidence From a Biomarker Validation Study in Zimbabwe.

/ / Faculty Research in Africa, Research

CGPH FACULTY:

DATE OF PUBLICATION: March 2014

REGION: Africa

REFERENCE: McCoy SI, Ralph LJ, Padian NS, Minnis AM. Are Hormonal Contraceptive Users More Likely to Misreport Unprotected Sex? Evidence From a Biomarker Validation Study in Zimbabwe. AIDS Behav. 2014 Mar 12.

SUMMARY/ABSTRACT: We analyzed biomarker validation data of unprotected sex from women in Zimbabwe to determine whether condom and sexual behavior misreporting differs between users of different contraceptive methods. Self-reported sexual behavior was compared with the presence of prostate-specific antigen (PSA) in vaginal fluid, a biomarker of semen exposure. Of the 195 women who were PSA positive, 94 (48 %) reported no sex or only condom-protected sex. Hormonal contraceptive users misreported sexual behavior less than women using non-hormonal methods (45 vs. 67 %, P = 0.03). This misclassification pattern could have implications on the elevated risk of HIV infection associated with hormonal contraception in some studies.

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