Determinants of differential HIV incidence among women in three southern African locations.

/ / Faculty Research in Africa, Research

CGPH FACULTY:Nancy Padia

DATE OF PUBLICATION:September 2011

REGION: Africa

REFERENCE: Mavedzenge SN, Weiss HA, Montgomery ET, Blanchard K, de Bruyn G, Ramjee G, Chipato T, Padian NS, Van Der Straten A. Determinants of differential HIV incidence among women in three southern African locations. J Acquir Immune Defic Syndr. 2011 Sep 1;58(1):89-99. doi: 10.1097/QAI.0b013e3182254038.

SUMMARY/ABSTRACT: We explored factors associated with differential HIV incidence among women participating in a HIV prevention trial in Harare, Durban, and Johannesburg. The trial had shown no effect of the intervention (diaphragm and lubricant gel) on HIV incidence. Important differences were seen in drivers of HIV incidence at the 3 study locations. Results from this analysis imply that targeted HIV programing could have a large impact on incident HIV infection in women, and that the most effective approach will likely vary based on knowledge of the local situation/epidemiology.

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